Epithelial mesenchymal-like transition occurs in a subset of cells in castration resistant prostate cancer bone metastases

TGFβ is a known driver of epithelial-mesenchymal transition (EMT) which is associated with tumor aggressiveness and metastasis. However, EMT has not been fully explored in clinical specimens of castration-resistant prostate cancer (CRPC) metastases. To assess EMT in CRPC, gene expression analysis wa...

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Pubblicato in:Clin Exp Metastasis
Autori principali: Haider, Maahum, Zhang, Xiaotun, Coleman, Ilsa, Ericson, Nolan, True, Lawrence D., Lam, Hung-Ming, Brown, Lisha G., Ketchanji, Melanie, Nghiem, Belinda, Lakely, Bryce, Coleman, Roger, Montgomery, Bruce, Lange, Paul H., Roudier, Martine, Higano, Celestia S., Bielas, Jason H., Nelson, Peter S., Vessella, Robert L., Morrissey, Colm
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4777655/
https://ncbi.nlm.nih.gov/pubmed/26667932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10585-015-9773-7
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