Epithelial mesenchymal-like transition occurs in a subset of cells in castration resistant prostate cancer bone metastases

TGFβ is a known driver of epithelial-mesenchymal transition (EMT) which is associated with tumor aggressiveness and metastasis. However, EMT has not been fully explored in clinical specimens of castration-resistant prostate cancer (CRPC) metastases. To assess EMT in CRPC, gene expression analysis wa...

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Détails bibliographiques
Publié dans:Clin Exp Metastasis
Auteurs principaux: Haider, Maahum, Zhang, Xiaotun, Coleman, Ilsa, Ericson, Nolan, True, Lawrence D., Lam, Hung-Ming, Brown, Lisha G., Ketchanji, Melanie, Nghiem, Belinda, Lakely, Bryce, Coleman, Roger, Montgomery, Bruce, Lange, Paul H., Roudier, Martine, Higano, Celestia S., Bielas, Jason H., Nelson, Peter S., Vessella, Robert L., Morrissey, Colm
Format: Artigo
Langue:Inglês
Publié: 2015
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4777655/
https://ncbi.nlm.nih.gov/pubmed/26667932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10585-015-9773-7
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