Epithelial mesenchymal-like transition occurs in a subset of cells in castration resistant prostate cancer bone metastases

TGFβ is a known driver of epithelial-mesenchymal transition (EMT) which is associated with tumor aggressiveness and metastasis. However, EMT has not been fully explored in clinical specimens of castration-resistant prostate cancer (CRPC) metastases. To assess EMT in CRPC, gene expression analysis wa...

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Detalhes bibliográficos
Publicado no:Clin Exp Metastasis
Main Authors: Haider, Maahum, Zhang, Xiaotun, Coleman, Ilsa, Ericson, Nolan, True, Lawrence D., Lam, Hung-Ming, Brown, Lisha G., Ketchanji, Melanie, Nghiem, Belinda, Lakely, Bryce, Coleman, Roger, Montgomery, Bruce, Lange, Paul H., Roudier, Martine, Higano, Celestia S., Bielas, Jason H., Nelson, Peter S., Vessella, Robert L., Morrissey, Colm
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4777655/
https://ncbi.nlm.nih.gov/pubmed/26667932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10585-015-9773-7
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