Загрузка...
Metastases and Colon Cancer Tumor Growth Display Divergent Responses to Modulation of Canonical WNT Signaling
Human colon cancers commonly harbor loss of function mutations in APC, a repressor of the canonical WNT pathway, thus leading to hyperactive WNT-TCF signaling. Re-establishment of Apc function in mice, engineered to conditionally repress Apc through RNAi, resolve the intestinal tumors formed due to...
Сохранить в:
| Опубликовано в: : | PLoS One |
|---|---|
| Главные авторы: | , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Public Library of Science
2016
|
| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4777488/ https://ncbi.nlm.nih.gov/pubmed/26939070 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0150697 |
| Метки: |
Добавить метку
Нет меток, Требуется 1-ая метка записи!
|