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Atg7 Knockdown Augments Concanavalin A-Induced Acute Hepatitis through an ROS-Mediated p38/MAPK Pathway

Concanavalin A (ConA), a T-cell mitogen that induces acute autoimmune hepatitis, is widely used to model pathophysiological processes of human acute autoimmune liver disease. Although autophagy has been extensively studied in the past decade, little is known about its molecular mechanism underlying...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Zhuang, Yan, Li, Yi, Li, Xuefeng, Xie, Qing, Wu, Min
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4777387/
https://ncbi.nlm.nih.gov/pubmed/26939081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0149754
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