Chargement en cours...

Largazole: From Discovery to Broad-Spectrum Therapy

The cyclic depsipeptide largazole from a cyanobacterium of the genus Symploca is a marine natural product with novel chemical scaffold and potently inhibits class I histone deacetylases (HDACs). Largazole possesses highly differential growth-inhibitory activity, preferentially targeting transformed...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Nat Prod Rep
Auteurs principaux: Hong, Jiyong, Luesch, Hendrik
Format: Artigo
Langue:Inglês
Publié: 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4777309/
https://ncbi.nlm.nih.gov/pubmed/22334030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c2np00066k
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!