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Taurolidine and congeners activate hTRPA1 but not hTRPV1 channels and stimulate CGRP release from mouse tracheal sensory nerves

Taurolidine has long been in clinical use as an antimicrobial irrigation that does not impede wound healing. It can even be administered intravenously (30 g/day) to treat sepsis or to exert newly recognized antineoplastic actions. Only one irritant effect is reported, that is, to temporarily induce...

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Pubblicato in:Pharmacol Res Perspect
Autori principali: Kichko, Tatjana I., Pfirrmann, Rolf W., Reeh, Peter W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4777271/
https://ncbi.nlm.nih.gov/pubmed/26977296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.204
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