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Taurolidine and congeners activate hTRPA1 but not hTRPV1 channels and stimulate CGRP release from mouse tracheal sensory nerves

Taurolidine has long been in clinical use as an antimicrobial irrigation that does not impede wound healing. It can even be administered intravenously (30 g/day) to treat sepsis or to exert newly recognized antineoplastic actions. Only one irritant effect is reported, that is, to temporarily induce...

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Vydáno v:Pharmacol Res Perspect
Hlavní autoři: Kichko, Tatjana I., Pfirrmann, Rolf W., Reeh, Peter W.
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4777271/
https://ncbi.nlm.nih.gov/pubmed/26977296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.204
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