T(H)17 cells promote microbial killing and innate immune sensing of DNA via interleukin 26

Interleukin 17–producing helper T cells (T(H)17 cells) have a major role in protection against infections and in mediating autoimmune diseases, yet the mechanisms involved are incompletely understood. We found that interleukin 26 (IL-26), a human T(H)17 cell–derived cytokine, is a cationic amphipath...

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Publicat a:Nat Immunol
Autors principals: Meller, Stephan, Domizio, Jeremy Di, Voo, Kui S, Friedrich, Heike C, Chamilos, Georgios, Ganguly, Dipyaman, Conrad, Curdin, Gregorio, Josh, Roy, Didier Le, Roger, Thierry, Ladbury, John E, Homey, Bernhard, Watowich, Stanley, Modlin, Robert L, Kontoyiannis, Dimitrios P, Liu, Yong-Jun, Arold, Stefan T, Gilliet, Michel
Format: Artigo
Idioma:Inglês
Publicat: 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4776746/
https://ncbi.nlm.nih.gov/pubmed/26168081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.3211
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