Deterministically patterned biomimetic human iPSC-derived hepatic model via rapid 3D bioprinting

The functional maturation and preservation of hepatic cells derived from human induced pluripotent stem cells (hiPSCs) are essential to personalized in vitro drug screening and disease study. Major liver functions are tightly linked to the 3D assembly of hepatocytes, with the supporting cell types f...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Ma, Xuanyi, Qu, Xin, Zhu, Wei, Li, Yi-Shuan, Yuan, Suli, Zhang, Hong, Liu, Justin, Wang, Pengrui, Lai, Cheuk Sun Edwin, Zanella, Fabian, Feng, Gen-Sheng, Sheikh, Farah, Chien, Shu, Chen, Shaochen
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2016
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4776497/
https://ncbi.nlm.nih.gov/pubmed/26858399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1524510113
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