Deterministically patterned biomimetic human iPSC-derived hepatic model via rapid 3D bioprinting

The functional maturation and preservation of hepatic cells derived from human induced pluripotent stem cells (hiPSCs) are essential to personalized in vitro drug screening and disease study. Major liver functions are tightly linked to the 3D assembly of hepatocytes, with the supporting cell types f...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Ma, Xuanyi, Qu, Xin, Zhu, Wei, Li, Yi-Shuan, Yuan, Suli, Zhang, Hong, Liu, Justin, Wang, Pengrui, Lai, Cheuk Sun Edwin, Zanella, Fabian, Feng, Gen-Sheng, Sheikh, Farah, Chien, Shu, Chen, Shaochen
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2016
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4776497/
https://ncbi.nlm.nih.gov/pubmed/26858399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1524510113
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