Deterministically patterned biomimetic human iPSC-derived hepatic model via rapid 3D bioprinting

The functional maturation and preservation of hepatic cells derived from human induced pluripotent stem cells (hiPSCs) are essential to personalized in vitro drug screening and disease study. Major liver functions are tightly linked to the 3D assembly of hepatocytes, with the supporting cell types f...

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Dettagli Bibliografici
Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Ma, Xuanyi, Qu, Xin, Zhu, Wei, Li, Yi-Shuan, Yuan, Suli, Zhang, Hong, Liu, Justin, Wang, Pengrui, Lai, Cheuk Sun Edwin, Zanella, Fabian, Feng, Gen-Sheng, Sheikh, Farah, Chien, Shu, Chen, Shaochen
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2016
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4776497/
https://ncbi.nlm.nih.gov/pubmed/26858399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1524510113
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