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Deterministically patterned biomimetic human iPSC-derived hepatic model via rapid 3D bioprinting

The functional maturation and preservation of hepatic cells derived from human induced pluripotent stem cells (hiPSCs) are essential to personalized in vitro drug screening and disease study. Major liver functions are tightly linked to the 3D assembly of hepatocytes, with the supporting cell types f...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Main Authors: Ma, Xuanyi, Qu, Xin, Zhu, Wei, Li, Yi-Shuan, Yuan, Suli, Zhang, Hong, Liu, Justin, Wang, Pengrui, Lai, Cheuk Sun Edwin, Zanella, Fabian, Feng, Gen-Sheng, Sheikh, Farah, Chien, Shu, Chen, Shaochen
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4776497/
https://ncbi.nlm.nih.gov/pubmed/26858399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1524510113
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