Crystallography captures catalytic steps in human methionine adenosyltransferase enzymes

The principal methyl donor of the cell, S-adenosylmethionine (SAMe), is produced by the highly conserved family of methionine adenosyltranferases (MATs) via an ATP-driven process. These enzymes play an important role in the preservation of life, and their dysregulation has been tightly linked to liv...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Murray, Ben, Antonyuk, Svetlana V., Marina, Alberto, Lu, Shelly C., Mato, Jose M., Hasnain, S. Samar, Rojas, Adriana L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2016
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4776477/
https://ncbi.nlm.nih.gov/pubmed/26858410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1510959113
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