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Crystallography captures catalytic steps in human methionine adenosyltransferase enzymes
The principal methyl donor of the cell, S-adenosylmethionine (SAMe), is produced by the highly conserved family of methionine adenosyltranferases (MATs) via an ATP-driven process. These enzymes play an important role in the preservation of life, and their dysregulation has been tightly linked to liv...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4776477/ https://ncbi.nlm.nih.gov/pubmed/26858410 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1510959113 |
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