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Methionine adenosyltransferases in cancers: Mechanisms of dysregulation and implications for therapy
Methionine adenosyltransferase genes encode enzymes responsible for the biosynthesis of S-adenosylmethionine, the principal biological methyl donor and precursor of polyamines and glutathione. Mammalian cells express three genes – MAT1A, MAT2A, and MAT2B – with distinct expression and functions. MAT...
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| Veröffentlicht in: | Exp Biol Med (Maywood) |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
SAGE Publications
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5788143/ https://ncbi.nlm.nih.gov/pubmed/29141455 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1535370217740860 |
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