Adaptive methylation regulation of p53 pathway in sympatric speciation of blind mole rats, Spalax

Epigenetic modifications play significant roles in adaptive evolution. The tumor suppressor p53, well known for controlling cell fate and maintaining genomic stability, is much less known as a master gene in environmental adaptation involving methylation modifications. The blind subterranean mole ra...

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Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Zhao, Yang, Tang, Jia-Wei, Yang, Zhi, Cao, Yi-Bin, Ren, Ji-Long, Ben-Abu, Yuval, Li, Kexin, Chen, Xue-Qun, Du, Ji-Zeng, Nevo, Eviatar
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2016
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4776458/
https://ncbi.nlm.nih.gov/pubmed/26858405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1522658112
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