Adaptive methylation regulation of p53 pathway in sympatric speciation of blind mole rats, Spalax

Epigenetic modifications play significant roles in adaptive evolution. The tumor suppressor p53, well known for controlling cell fate and maintaining genomic stability, is much less known as a master gene in environmental adaptation involving methylation modifications. The blind subterranean mole ra...

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Dettagli Bibliografici
Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Zhao, Yang, Tang, Jia-Wei, Yang, Zhi, Cao, Yi-Bin, Ren, Ji-Long, Ben-Abu, Yuval, Li, Kexin, Chen, Xue-Qun, Du, Ji-Zeng, Nevo, Eviatar
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2016
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4776458/
https://ncbi.nlm.nih.gov/pubmed/26858405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1522658112
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