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Adaptive methylation regulation of p53 pathway in sympatric speciation of blind mole rats, Spalax

Epigenetic modifications play significant roles in adaptive evolution. The tumor suppressor p53, well known for controlling cell fate and maintaining genomic stability, is much less known as a master gene in environmental adaptation involving methylation modifications. The blind subterranean mole ra...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Zhao, Yang, Tang, Jia-Wei, Yang, Zhi, Cao, Yi-Bin, Ren, Ji-Long, Ben-Abu, Yuval, Li, Kexin, Chen, Xue-Qun, Du, Ji-Zeng, Nevo, Eviatar
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4776458/
https://ncbi.nlm.nih.gov/pubmed/26858405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1522658112
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