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2-thio-6-azauridine inhibits Vpu mediated BST-2 degradation

BACKGROUD: BST-2 is an interferon-induced host restriction factor that inhibits the release of diverse mammalian enveloped viruses from infected cells by physically trapping the newly formed virions onto the host cell surface. Human Immunodeficiency Virus-1 (HIV-1) encodes an accessory protein Vpu t...

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Bibliographic Details
Published in:Retrovirology
Main Authors: Zhang, Quan, Mi, Zeyun, Huang, Yuming, Ma, Ling, Ding, Jiwei, Wang, Jing, Zhang, Yongxin, chen, Yang, Zhou, Jinming, Guo, Fei, Li, Xiaoyu, Cen, Shan
Format: Artigo
Language:Inglês
Published: BioMed Central 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4776379/
https://ncbi.nlm.nih.gov/pubmed/26935098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12977-016-0247-z
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