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Structural Insight into Substrate Selectivity of Erwinia chrysanthemil-Asparaginase
[Image: see text] l-Asparaginases of bacterial origin are a mainstay of acute lymphoblastic leukemia treatment. The mechanism of action of these enzyme drugs is associated with their capacity to deplete the amino acid l-asparagine from the blood. However, clinical use of bacterial l-asparaginases is...
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| Publié dans: | Biochemistry |
|---|---|
| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American
Chemical Society
2016
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| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4776285/ https://ncbi.nlm.nih.gov/pubmed/26855287 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.5b01351 |
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