Protein kinase A antagonizes platelet-derived growth factor-induced signaling by mitogen-activated protein kinase in human arterial smooth muscle cells.

Stimulation of aortic smooth muscle cells with platelet-derived growth factor BB homodimer (PDGF-BB) leads to the rapid activation of mitogen-activated protein kinase (MAPK) and MAPK kinase (MAPKK). Compounds that increase cAMP and activate protein kinase A (PKA)--prostaglandin E2, isoproterenol, ch...

Full description

Saved in:
Bibliographic Details
Main Authors: Graves, L M, Bornfeldt, K E, Raines, E W, Potts, B C, Macdonald, S G, Ross, R, Krebs, E G
Format: Artigo
Language:Inglês
Published: 1993
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC47762/
https://ncbi.nlm.nih.gov/pubmed/7694289
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items