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Deciphering DNA replication dynamics in eukaryotic cell populations in relation with their averaged chromatin conformations

We propose a non-local model of DNA replication that takes into account the observed uncertainty on the position and time of replication initiation in eukaryote cell populations. By picturing replication initiation as a two-state system and considering all possible transition configurations, and by...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Goldar, A., Arneodo, A., Audit, B., Argoul, F., Rappailles, A., Guilbaud, G., Petryk, N., Kahli, M., Hyrien, O.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4776152/
https://ncbi.nlm.nih.gov/pubmed/26935043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep22469
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