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Mutations That Enhance the Ciprofloxacin Resistance of Escherichia coli with qnrA1

Plasmid-mediated qnr genes provide only a modest decrease in quinolone susceptibility but facilitate the selection of higher-level resistance. In Escherichia coli strain J53 without qnr, ciprofloxacin resistance often involves mutations in the GyrA subunit of DNA gyrase. Mutations in gyrA were absen...

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Bibliographic Details
Published in:Antimicrob Agents Chemother
Main Authors: Vinué, Laura, Corcoran, Marian A., Hooper, David C., Jacoby, George A.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4776012/
https://ncbi.nlm.nih.gov/pubmed/26711751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02167-15
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