Novel Bone-Targeting Agent for Enhanced Delivery of Vancomycin to Bone

We examined the pharmacokinetic properties of vancomycin conjugated to a bone-targeting agent (BT) with high affinity for hydroxyapatite after systemic intravenous administration. The results confirm enhanced persistence of BT-vancomycin in plasma and enhanced accumulation in bone relative to vancom...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Antimicrob Agents Chemother
Main Authors: Albayati, Zaineb A. F., Sunkara, Manjula, Schmidt-Malan, Suzannah M., Karau, Melissa J., Morris, Andrew J., Steckelberg, James M., Patel, Robin, Breen, Philip J., Smeltzer, Mark S., Taylor, K. Grant, Merten, Kevyn E., Pierce, William M., Crooks, Peter A.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2016
Teme:
Experimental Therapeutics
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4776008/
https://ncbi.nlm.nih.gov/pubmed/26666918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01609-15
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki