Linezolid Is Superior to Vancomycin in Experimental Pneumonia Caused by Superantigen-Producing Staphylococcus aureus in HLA Class II Transgenic Mice

Superantigens (SAg), the potent activators of the immune system, are important determinants of Staphylococcus aureus virulence and pathogenicity. Superior response to SAg in human leukocyte antigen (HLA)-DR3 transgenic mice rendered them more susceptible than C57BL/6 mice to pneumonia caused by SAg-...

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Autores principales: Karau, Melissa J., Tilahun, Ashenafi Y., Schmidt, Suzannah M., Clark, Chad R., Patel, Robin, Rajagopalan, Govindarajan
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2012
Materias:
Experimental Therapeutics
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3457354/
https://ncbi.nlm.nih.gov/pubmed/22850509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01080-12
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