Population Pharmacokinetics of Colistin Methanesulfonate and Colistin in Critically Ill Patients with Acute Renal Failure Requiring Intermittent Hemodialysis

Colistin is increasingly used as a last option for the treatment of severe infections due to Gram-negative bacteria in critically ill patients requiring intermittent hemodialysis (HD) for acute renal failure. Our objective was to characterize the pharmacokinetics (PK) of colistin and its prodrug col...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Jacobs, M., Grégoire, N., Mégarbane, B., Gobin, P., Balayn, D., Marchand, S., Mimoz, O., Couet, W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4775947/
https://ncbi.nlm.nih.gov/pubmed/26729492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01868-15
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