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Inhibition of Hippocampal Regeneration by Adjuvant Dexamethasone in Experimental Infant Rat Pneumococcal Meningitis

Pneumococcal meningitis (PM) causes neurological sequelae in up to half of surviving patients. Neuronal damage associated with poor outcome is largely mediated by the inflammatory host response. Dexamethasone (DXM) is used as an adjuvant therapy in adult PM, but its efficacy in the treatment of pneu...

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Publicado en:Antimicrob Agents Chemother
Main Authors: Bally, Lia, Grandgirard, Denis, Leib, Stephen L.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4775913/
https://ncbi.nlm.nih.gov/pubmed/26824948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02429-15
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