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Inhibition of Hippocampal Regeneration by Adjuvant Dexamethasone in Experimental Infant Rat Pneumococcal Meningitis

Pneumococcal meningitis (PM) causes neurological sequelae in up to half of surviving patients. Neuronal damage associated with poor outcome is largely mediated by the inflammatory host response. Dexamethasone (DXM) is used as an adjuvant therapy in adult PM, but its efficacy in the treatment of pneu...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Bally, Lia, Grandgirard, Denis, Leib, Stephen L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4775913/
https://ncbi.nlm.nih.gov/pubmed/26824948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02429-15
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