Sulforaphane prevents rat cardiomyocytes from hypoxia/reoxygenation injury in vitro via activating SIRT1 and subsequently inhibiting ER stress

AIM: Sulforaphane (SFN), a natural dietary isothiocyanate, is found to exert beneficial effects for cardiovascular diseases. This study aimed to investigate the mechanisms underlying the protective effects of SFN in a model of myocardial hypoxia/reoxygenation (H/R) injury in vitro. METHODS: Cultured...

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Detalhes bibliográficos
Publicado no:Acta Pharmacol Sin
Main Authors: Li, Yun-peng, Wang, Shu-lin, Liu, Bei, Tang, Lu, Kuang, Rong-ren, Wang, Xian-bao, Zhao, Cong, Song, Xu-dong, Cao, Xue-ming, Wu, Xiang, Yang, Ping-zhen, Wang, Li-zi, Chen, Ai-hua
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4775847/
https://ncbi.nlm.nih.gov/pubmed/26775664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2015.130
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