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Thrombin Aggravates Hypoxia/Reoxygenation Injury of Cardiomyocytes by Activating an Autophagy Pathway-Mediated by SIRT1
BACKGROUND: Acute myocardial infarction is the leading cause of mortality among adults worldwide. The present study aimed to investigate the role and mechanism of thrombin and SIRT1 in hypoxia/reoxygenation (H/R) injury. MATERIAL/METHODS: H9c2 cardiomyocytes were used to create an H/R model to simul...
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| 出版年: | Med Sci Monit |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
International Scientific Literature, Inc.
2021
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8098101/ https://ncbi.nlm.nih.gov/pubmed/33931577 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.928480 |
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