Sevoflurane postconditioning alleviates hypoxia-reoxygenation injury of cardiomyocytes by promoting mitochondrial autophagy through the HIF-1/BNIP3 signaling pathway

BACKGROUND: Sevoflurane postconditioning (SpostC) can alleviate hypoxia-reoxygenation injury of cardiomyocytes; however, the specific mechanism remains unclear. This study aimed to investigate whether SpostC promotes mitochondrial autophagy through the hypoxia-inducible factor-1 (HIF-1)/BCL2/adenovi...

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Publicat a:PeerJ
Autors principals: Yang, Long, Wu, Jianjiang, Xie, Peng, Yu, Jin, Li, Xin, Wang, Jiang, Zheng, Hong
Format: Artigo
Idioma:Inglês
Publicat: PeerJ Inc. 2019
Matèries:
Anesthesiology and Pain Management
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6596409/
https://ncbi.nlm.nih.gov/pubmed/31275755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.7165
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