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Differential modulation of GABA(A) and NMDA receptors by α7-nicotinic receptor desensitization in cultured rat hippocampal neurons

AIM: To explore the modulatory effect of desensitized α7-containing nicotinic receptors (α7-nAChRs) on excitatory and inhibitory amino acid receptors in cultured hippocampal neurons and to identify the mechanism underlying this effect. METHODS: Whole-cell patch-clamp recordings were performed on cul...

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Detalhes bibliográficos
Publicado no:Acta Pharmacol Sin
Main Authors: Shen, Lei, Cui, Wen-yu, Chen, Ru-zhu, Wang, Hai
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4775840/
https://ncbi.nlm.nih.gov/pubmed/26806304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2015.106
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