Differential Modulation of GABAA and NMDA Receptors by an α7-nicotinic Acetylcholine Receptor Agonist in Chronic Glaucoma

Presynaptic modulation of γ-aminobutyric acid (GABA) release by an alpha7 nicotinic acetylcholine receptor (α7-nAChR) agonist promotes retinal ganglion cell (RGC) survival and function, as suggested by a previous study on a chronic glaucomatous model from our laboratory. However, the role of excitat...

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Detalhes bibliográficos
Main Authors: Xujiao Zhou, Yuan Zong, Rong Zhang, Xuejin Zhang, Shenghai Zhang, Jihong Wu, Xinghuai Sun
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017-12-01
Colecção:Frontiers in Molecular Neuroscience
Assuntos:
α7-nAChR
GABAA receptors
NMDA receptors
neuroprotection
chronic glaucoma
Acesso em linha:http://journal.frontiersin.org/article/10.3389/fnmol.2017.00422/full
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