Herbacetin is a novel allosteric inhibitor of ornithine decarboxylase with antitumor activity

Ornithine decarboxylase (ODC) is a rate-limiting enzyme in the first step of polyamine biosynthesis that is associated with cell growth and tumor formation. Existing catalytic inhibitors of ODC have lacked efficacy in clinical testing or displayed unacceptable toxicity. In this study, we report the...

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Xehetasun bibliografikoak
Argitaratua izan da:Cancer Res
Egile Nagusiak: Kim, Dong Joon, Roh, Eunmiri, Lee, Mee-Hyun, Oi, Naomi, Lim, Do Young, Kim, Myoung Ok, Cho, Young-Yeon, Pugliese, Angelo, Shim, Jung-Hyun, Chen, Hanyong, Cho, Eun Jin, Kim, Jong-Eun, Kang, Sun Chul, Paul, Souren, Kang, Hee Eun, Jung, Ji Won, Lee, Sung-Young, Kim, Sung-Hyun, Reddy, Kanamata, Yeom, Young Il, Bode, Ann M, Dong, Zigang
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2015
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4775427/
https://ncbi.nlm.nih.gov/pubmed/26676750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-15-0442
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