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CInQ-03, a novel allosteric MEK inhibitor, suppresses cancer growth in vitro and in vivo
The mitogen-activated protein kinase kinase 1 and 2 signaling pathway is a major component of the RAS (Rat sarcoma)/RAF (Radpidly accelerated fibrosarcoma)/MEK (mitogen-activated protein kinase kinase)/ERKs (Extracellular signal-regulated kinases) signaling axis that regulates tumorigenesis and canc...
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| Autori principali: | , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3643416/ https://ncbi.nlm.nih.gov/pubmed/23354306 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgt015 |
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