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Selective binding of AIRAPL tandem UIMs to Lys48- linked tri-ubiquitin chains
Lys48-linked ubiquitin chains act as the main targeting signals for protein degradation by the proteasome. Here we report selective binding of AIRAPL, a protein that associates with the proteasome upon exposure to arsenite, to Lys48-linked tri-ubiquitin chains. AIRAPL comprises two ubiquitin-interac...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Structure |
|---|---|
| Κύριοι συγγραφείς: | , , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2016
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4775417/ https://ncbi.nlm.nih.gov/pubmed/26876100 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2015.12.017 |
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