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Development and Evaluation of Biodegradable Particles Co-loaded with Antigen and the Toll-like Receptor Agonist, Pentaerythritol Lipid A, as a Cancer Vaccine

Immune adjuvants are important components of current and prospective cancer vaccines. In this study we aimed at evaluating the use of a synthetic lipid A derivative, pentaerythritol lipid A (PET lipid A), loaded into poly(lactic-co-glycolic acid) (PLGA) particles, as a potential cancer vaccine adjuv...

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Detalhes bibliográficos
Publicado no:J Pharm Sci
Main Authors: Ahmed, Kawther K., Geary, Sean M., Salem, Aliasger K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4775392/
https://ncbi.nlm.nih.gov/pubmed/26886334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.xphs.2015.11.042
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