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Biodegradable Particles as Vaccine Delivery Systems: Size Matters

Poly(lactide-co-glycolide) (PLGA) particles have strong potential as antigen delivery systems. The size of PLGA particles used to vaccinate mice can affect the magnitude of the antigen-specific immune response stimulated. In this study, we fabricated and characterized 17 μm, 7 μm, 1 μm, and 300 nm P...

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Autors principals: Joshi, Vijaya B., Geary, Sean M., Salem, Aliasger K.
Format: Artigo
Idioma:Inglês
Publicat: Springer US 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3535111/
https://ncbi.nlm.nih.gov/pubmed/23054976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-012-9418-6
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