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Pentaerythritol-based lipid A bolsters the antitumor efficacy of a polyanhydride particle-based cancer vaccine

The primary objective of this study was to enhance the antitumor efficacy of a model cancer vaccine through co-delivery of pentaerythritol lipid A (PELA), an immunological adjuvant, and a model tumor antigen, ovalbumin (OVA), separately loaded into polyanhydride particles (PA). In vitro experiments...

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Detalhes bibliográficos
Publicado no:Nanomedicine
Main Authors: Wafa, Emad I., Geary, Sean M., Ross, Kathleen A., Goodman, Jonathan T., Narasimhan, Balaji, Salem, Aliasger K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6814548/
https://ncbi.nlm.nih.gov/pubmed/31319179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nano.2019.102055
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