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Munc18-1 and the Syntaxin-1 N-terminus Regulate Open-Closed States in a t-SNARE complex

Neuronal exocytosis is mediated by SNARE proteins, which assemble into a highly stable four helical bundle in a process that is not well-understood. In the present study, EPR spectroscopy was used to examine how the t-SNAREs syntaxin and SNAP25 assemble in the presence and absence of the regulatory...

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Detalhes bibliográficos
Publicado no:Structure
Main Authors: Dawidowski, Damian, Cafiso, David S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4775345/
https://ncbi.nlm.nih.gov/pubmed/26876096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2016.01.005
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