Emodin enhances the demethylation by 5-Aza-CdR of pancreatic cancer cell tumor-suppressor genes P16, RASSF1A and ppENK

5-Aza-2′-deoxycytidine (5-Aza-CdR) is currently acknowledged as a demethylation drug, and causes a certain degree of demethylation in a variety of cancer cells, including pancreatic cancer cells. Emodin, a traditional Chinese medicine (TCM), is an effective monomer extracted from rhubarb and has bee...

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Pubblicato in:Oncol Rep
Autori principali: PAN, FENG-PING, ZHOU, HONG-KUN, BU, HE-QI, CHEN, ZI-QIANG, ZHANG, HAO, XU, LU-PING, TANG, JIAN, YU, QING-JIANG, CHU, YONG-QUAN, PAN, JIE, FEI, YONG, LIN, SHENG-ZHANG, LIU, DIAN-LEI, CHEN, LIANG
Natura: Artigo
Lingua:Inglês
Pubblicazione: D.A. Spandidos 2016
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4774670/
https://ncbi.nlm.nih.gov/pubmed/26782786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2016.4554
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