Reduced Endoglin Activity Limits Cardiac Fibrosis and Improves Survival in Heart Failure

BACKGROUND: Heart failure is a major cause of morbidity and mortality worldwide. The ubiquitously expressed cytokine, transforming growth factor beta-1 (TGFβ1), promotes cardiac fibrosis, an important component of progressive heart failure. Membrane-associated endoglin is a co-receptor for TGFβ1 sig...

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Detaylı Bibliyografya
Yayımlandı:Circulation
Asıl Yazarlar: Kapur, Navin K., Wilson, Szuhuei, Yunis, Adil A., Qiao, Xiaoying, Mackey, Emily, Paruchuri, Vikram, Baker, Corey, Aronovitz, Mark J., Karumanchi, S. Ananth, Letarte, Michelle, Kass, David A., Mendelsohn, Michael E., Karas, Richard H.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2012
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4774533/
https://ncbi.nlm.nih.gov/pubmed/22592898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.111.080002
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