Reduced Endoglin Activity Limits Cardiac Fibrosis and Improves Survival in Heart Failure

BACKGROUND: Heart failure is a major cause of morbidity and mortality worldwide. The ubiquitously expressed cytokine, transforming growth factor beta-1 (TGFβ1), promotes cardiac fibrosis, an important component of progressive heart failure. Membrane-associated endoglin is a co-receptor for TGFβ1 sig...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Circulation
Egile Nagusiak: Kapur, Navin K., Wilson, Szuhuei, Yunis, Adil A., Qiao, Xiaoying, Mackey, Emily, Paruchuri, Vikram, Baker, Corey, Aronovitz, Mark J., Karumanchi, S. Ananth, Letarte, Michelle, Kass, David A., Mendelsohn, Michael E., Karas, Richard H.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2012
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4774533/
https://ncbi.nlm.nih.gov/pubmed/22592898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.111.080002
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