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Assessment of the Cytotoxic and Apoptotic Effects of Chaetominine in a Human Leukemia Cell Line

Chaetominine is a quinazoline alkaloid originating from the endophytic fungus Aspergillus fumigatus CY018. In this study, we showed evidence that chaetominine has cytotoxic and apoptotic effects on human leukemia K562 cells and investigated the pathway involved in chaetominine-induced apoptosis in d...

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Detalhes bibliográficos
Publicado no:Biomol Ther (Seoul)
Main Authors: Yao, Jingyun, Jiao, Ruihua, Liu, Changqing, Zhang, Yupeng, Yu, Wanguo, Lu, Yanhua, Tan, Renxiang
Formato: Artigo
Idioma:Inglês
Publicado em: The Korean Society of Applied Pharmacology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4774495/
https://ncbi.nlm.nih.gov/pubmed/26902083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4062/biomolther.2015.093
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