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Assessment of the Cytotoxic and Apoptotic Effects of Chaetominine in a Human Leukemia Cell Line

Chaetominine is a quinazoline alkaloid originating from the endophytic fungus Aspergillus fumigatus CY018. In this study, we showed evidence that chaetominine has cytotoxic and apoptotic effects on human leukemia K562 cells and investigated the pathway involved in chaetominine-induced apoptosis in d...

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Bibliografski detalji
Izdano u:Biomol Ther (Seoul)
Glavni autori: Yao, Jingyun, Jiao, Ruihua, Liu, Changqing, Zhang, Yupeng, Yu, Wanguo, Lu, Yanhua, Tan, Renxiang
Format: Artigo
Jezik:Inglês
Izdano: The Korean Society of Applied Pharmacology 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4774495/
https://ncbi.nlm.nih.gov/pubmed/26902083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4062/biomolther.2015.093
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