Nur77-deficiency in bone marrow-derived macrophages modulates inflammatory responses, extracellular matrix homeostasis, phagocytosis and tolerance

BACKGROUND: The nuclear orphan receptor Nur77 (NR4A1, TR3, or NGFI-B) has been shown to modulate the inflammatory response of macrophages. To further elucidate the role of Nur77 in macrophage physiology, we compared the transcriptome of bone marrow-derived macrophages (BMM) from wild-type (WT) and N...

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Vydáno v:BMC Genomics
Hlavní autoři: Hamers, Anouk A. J., Argmann, Carmen, Moerland, Perry D., Koenis, Duco S., Marinković, Goran, Sokolović, Milka, de Vos, Alex F., de Vries, Carlie J. M., van Tiel, Claudia M.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2016
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4774191/
https://ncbi.nlm.nih.gov/pubmed/26932821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-016-2469-9
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