The immunity-related GTPase Irga6 dimerizes in a parallel head-to-head fashion

BACKGROUND: The immunity-related GTPases (IRGs) constitute a powerful cell-autonomous resistance system against several intracellular pathogens. Irga6 is a dynamin-like protein that oligomerizes at the parasitophorous vacuolar membrane (PVM) of Toxoplasma gondii leading to its vesiculation. Based on...

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Enregistré dans:
Détails bibliographiques
Publié dans:BMC Biol
Auteurs principaux: Schulte, Kathrin, Pawlowski, Nikolaus, Faelber, Katja, Fröhlich, Chris, Howard, Jonathan, Daumke, Oliver
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2016
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4774019/
https://ncbi.nlm.nih.gov/pubmed/26934976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12915-016-0236-7
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