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Innate myeloid cell TNFR1 mediates first line defence against primary Mycobacterium tuberculosis infection.

TNF is crucial for controlling Mycobacterium tuberculosis infection and understanding how will help immunomodulating the host response. Here we assessed the contribution of TNFR1 pathway from innate myeloid versus T cells. We first established the prominent role of TNFR1 in haematopoietic cells for...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Segueni, Noria, Benmerzoug, Sulayman, Rose, Stéphanie, Gauthier, Amandine, Bourigault, Marie-Laure, Reverchon, Flora, Philippeau, Amandine, Erard, François, Le Bert, Marc, Bouscayrol, Hélène, Wachter, Thierry, Garcia, Irène, Kollias, George, Jacobs, Muazzam, Ryffel, Bernhard, Quesniaux, Valerie F.J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4773807/
https://ncbi.nlm.nih.gov/pubmed/26931771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep22454
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