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Persistent p55TNFR expression impairs T cell responses during chronic tuberculosis and promotes reactivation

The pleiotropic activities of TNF are mediated by two structurally related but functionally distinct type I transmembrane receptors, p55TNFR and p75TNFR expressed in most cell types, that can be cleaved and act as TNF scavengers. Here, we investigated the effect of persistent p55TNFR cell surface ex...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Dambuza, Ivy M., Keeton, Roanne, Hsu, Nai-Jen, Allie, Nasiema, Quesniaux, Valérie F. J., Ryffel, Bernhard, Jacobs, Muazzam
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5171238/
https://ncbi.nlm.nih.gov/pubmed/27995986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep39499
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