Src regulates insulin secretion and glucose metabolism by influencing subcellular localization of glucokinase in pancreatic β‐cells

AIMS/INTRODUCTION: Src, a non‐receptor tyrosine kinase, regulates a wide range of cellular functions, and hyperactivity of Src is involved in impaired glucose metabolism in pancreatic β‐cells. However, the physiological role of Src in glucose metabolism in normal, unstressed β‐cells remains unclear....

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Detalhes bibliográficos
Publicado no:J Diabetes Investig
Main Authors: Sato, Hiroki, Nagashima, Kazuaki, Ogura, Masahito, Sato, Yuichi, Tahara, Yumiko, Ogura, Kasane, Yamano, Gen, Sugizaki, Kazu, Fujita, Naotaka, Tatsuoka, Hisato, Usui, Ryota, Mukai, Eri, Fujimoto, Shimpei, Inagaki, Nobuya
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4773676/
https://ncbi.nlm.nih.gov/pubmed/27042268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jdi.12407
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