Src regulates insulin secretion and glucose metabolism by influencing subcellular localization of glucokinase in pancreatic β‐cells

AIMS/INTRODUCTION: Src, a non‐receptor tyrosine kinase, regulates a wide range of cellular functions, and hyperactivity of Src is involved in impaired glucose metabolism in pancreatic β‐cells. However, the physiological role of Src in glucose metabolism in normal, unstressed β‐cells remains unclear....

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Diabetes Investig
Prif Awduron: Sato, Hiroki, Nagashima, Kazuaki, Ogura, Masahito, Sato, Yuichi, Tahara, Yumiko, Ogura, Kasane, Yamano, Gen, Sugizaki, Kazu, Fujita, Naotaka, Tatsuoka, Hisato, Usui, Ryota, Mukai, Eri, Fujimoto, Shimpei, Inagaki, Nobuya
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2015
Pynciau:
Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4773676/
https://ncbi.nlm.nih.gov/pubmed/27042268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jdi.12407
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