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BTG2 bridges PABPC1 RNA-binding domains and CAF1 deadenylase to control cell proliferation

While BTG2 plays an important role in cellular differentiation and cancer, its precise molecular function remains unclear. BTG2 interacts with CAF1 deadenylase through its APRO domain, a defining feature of BTG/Tob factors. Our previous experiments revealed that expression of BTG2 promoted mRNA poly...

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Publicat a:Nat Commun
Autors principals: Stupfler, Benjamin, Birck, Catherine, Séraphin, Bertrand, Mauxion, Fabienne
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4773420/
https://ncbi.nlm.nih.gov/pubmed/26912148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10811
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