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X-ray structure and activity of the yeast Pop2 protein: a nuclease subunit of the mRNA deadenylase complex

In Saccharomyces cerevisiae, a large complex, known as the Ccr4–Not complex, containing two nucleases, is responsible for mRNA deadenylation. One of these nucleases is called Pop2 and has been identified by similarity with PARN, a human poly(A) nuclease. Here, we present the crystal structure of the...

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Detalhes bibliográficos
Main Authors: Thore, Stéphane, Mauxion, Fabienne, Séraphin, Bertrand, Suck, Dietrich
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1326415/
https://ncbi.nlm.nih.gov/pubmed/14618157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7400020
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